​Celiac Disease Patients May Soon Test Gluten In Food

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October 21, 2021

Celiac disease patients may soon have a way to use a sensor to test for gluten in food, with the help by researchers in Spain. Maria Isabel Pividori from the Sensors and Biosensors Group at the Universitat Autònoma de Barcelona confirmed the development.

Pividori calls it the “electrochemical magneto immunosensor for the sensitive detection of gliadin - and small gliadin fragments - in natural or pretreated foods.” Gliadin is the main protein trigger for the disease.

The celiac sensor is an important step toward addressing “increasing demand for rapid, simple and low cost techniques for accurate food analysis in decentralized analytical situations,” said Pividori.

The celiac research team measured the performance of the electrochemical immuno-sensor by comparing it with a new magneto-ELISA, using optical detection performed on the Sunrise plate reader.

The team conducted ELISAs in 96-well microplates, using a magnetic separation plate to isolate the supernatant before measuring the absorbance in the Sunrise reader.

This enabled the team to conduct immunoassays in a number of various formats for multiple applications - such as evaluating protein coupling to magnetic beads and nanoparticles - as well as allowing assessment of different transducer materials for bio-sensing purposes.

Because it offers “a quick and easy way to optimize reagents and assay parameters,” Pividori calls the Sunrise “ideal for research applications.”

So just how far off is a commercially viable device that will allow people with celiac disease to test gluten levels in their food? Only time will tell, but stay tuned for more developments as researchers try to deliver such a device.

Meantime, let us know what you think. Would you like a device that could easily and accurately test food for gluten? Would such a device make your gluten-free life better or easier? Comment below to let us know your thoughts.