Obesity Cause – It is estimated that over two-thirds of Americans are either overweight or considered obese, and now new research may prove some have a hereditary mutilation to blame for the cause.
Dr. Gozoh Tsujimoto, a professor at Kyoto University’s department of genomic drug discovery science in Japan, co-authored the study of genetic mutilation in mice. The study proved that with the absence of a genetic component known as GPR120, that communicates with the body to control appetite and how many fat cells to produce, those mice gained 10% more weight.
Dr. Tsujimoto is quick to point out that more research needs to be done as animal trial results don’t always mean the same for humans. Furthermore, the genetic mutilation has been researched in some Europeans, and those found to be missing the gene were more likely to be obese, according to researchers.
“Our study for the first time demonstrated the gene responsible for diet-induced obesity,” Tsujimoto said.
However, if the same hereditary mutilation is concretely linked to human obesity, it could lead to doctors recommending the right diets, and the production of medicine for those who suffer from the absence of the genetic make-up to help control their weight.
It could create “a new avenue for personalized health care,” Tsujimoto said.
Ruth Loos, who is the director of Genetics of Obesity and Related Metabolic Traits at Mount Sinai School of Medicine in New York City, says, “This is only the beginning of likely many years of research to disentangle the physiological mechanisms that lie behind the link between this gene and obesity risk. It is only when we understand the physiology and biology better than one can start thinking of developing a drug.”